Tevin Coleman (knee) ruled out again for 49ers in Week 10

San Francisco 49ers running back Tevin Coleman (knee) is out for Week 10 against the New Orleans Saints on Sunday.

What It Means:

Coleman will miss a second consecutive game after not practicing all week. Raheem Mostert (ankle) also remains sidelined, leaving backfield responsibilities to Jerick McKinnon and JaMycal Hasty. NBC Sports' Matt Maiocco expects McKinnon to "get a lot of work" versus the Saints. Coleman should be able to return following the 49ers' Week 11 bye.

McKinnon is the RB11 and Hasty is the RB41 in numberFire's Week 10 fantasy rankings. McKinnon is averaging 15.2 FanDuel points and has hit double-digits six times in the games he's played at least half of the snaps. He has an attractive pass-catching matchup against Kwon Alexander, Pro Football Focus' No. 50 coverage corner out of 65 linebackers with at least 250 snaps this season.