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49ers' George Kittle (groin) officially inactive for Week 2

The San Francisco 49ers have ruled out tight end George Kittle for their Week 2 game against the Seattle Seahawks.

What It Means:

Kittle will miss his second straight game as he continues dealing with a groin injury. We'll have to wait and see if he can make his season debut in Week 3. In the meantime, expect the 49ers' passing game to run through Deebo Samuel and Brandon Aiyuk.

Our models project Samuel to lead the way for the 49ers this week, with 14.3 fantasy points. He has an $8,000 salary on FanDuel, while Aiyuk has a $5,700 salary and is projected for 7.4 fantasy points.