NFL Betting Guide: Week 16

Welcome to the penultimate week of the NFL regular season.

According to oddsFire, seven games this week have lines available that are within four points. Six of the other games have spreads where a team is favored by a touchdown or more. With such polarizing spreads, bettors might need help deciding what to wager on.

Luckily, numberFire has built comprehensive algorithms to pinpoint the bets with the highest probability of returning money, whether you are betting on the total, spread, or moneyline. For those new to numberFire, we use a five-star system to show which bets you should be targeting on any week. Stars represent how much you should risk on a wager relative to what you would normally bet.

For example, if you would usually bet $110 to win $100 on a -110 spread wager, if we give a 3-star ranking, we suggest risking three times that amount: $330 to win $300.

Using our models as a guide, let's take a look at the best bets for Week 15.

Please note that lines are subject to change throughout the day after this article is published. Please check here to make sure you're seeing the most updated information.

Buffalo Bills at New England Patriots