Houston Texans running back Dameon Pierce (ankle) will not play in Week 15's contest against the Kansas City Chiefs.

Houston Texans running back Dameon Pierce has been diagnosed with a high ankle sprain.

Houston Texans head coach Lovie Smith told reporters Monday that running back Dameon Pierce (ankle) will undergo an MRI following the team's Week 14 loss to the Dallas Cowboys.

With Houston a 16.5-point underdog against an elite Dallas defense, Dameon Pierce is a tough sell this week. Who else should you be wary of for Sunday's main slate?

Tom Brady and the Buccaneers have won three of their past four games. How are they performing from a fantasy football standpoint, and what does it mean for Week 14 lineup decisions?

What should fantasy football managers do about Dameon Pierce?

The running back landscape is shifting for a lot of teams. How should we view certain backfields? And who else can we start this week?

A lot of Commanders are in the start-or-sit discussion. How should we handle them -- and all relevant players -- in Week 12?

Justin Fields is unstoppable right now. How has that impacted his pass-catchers? See how everyone rates out for Week 11.

Kyren Williams could hop into a prominent role with the Rams sooner than it appears. Which other predictions can we make for this weekend's action?