New York Giants running back Saquon Barkley will play Sunday in the team's Week 6 game against the Buffalo Bills.

ESPN's Adam Schefter reports that the New York Giants are "hopeful" and "optimistic" that star running back Saquon Barkley (ankle) will play in the team's Week 6 game against the Buffalo Bills.

New York Giants running back Saquon Barkley (ankle) was limited at Thursday's practice for Week 6 against the Buffalo Bills on Sunday night.

New York Giants running back Saquon Barkley (ankle) was limited at Wednesday's practice for Week 6 against the Buffalo Bills on Sunday night.

New York Giants running back Saquon Barkley (ankle) will be "ramped up" in practice on Wednesday, per head coach Brian Daboll.

The New York Giants have ruled out running back Saquon Barkley (ankle) for their Week 5 game against the Miami Dolphins.

The New York Giants are not expected to have running back Saquon Barkley (ankle) available for their Week 5 game against the Miami Dolphins.

New York Giants running back Saquon Barkley (ankle) is officially questionable for Week 5 against the Miami Dolphins on Sunday.

New York Giants running back Saquon Barkley (ankle) could be a game-time decision on Sunday in Week 5 against the Miami Dolphins, per head coach Brian Daboll.

New York Giants running back Saquon Barkley (ankle) is listed as a limited participant on Wednesday's injury report for Week 5 against the Miami Dolphins.