With Trey Lance hurt, a new sheriff has stepped in under center for San Francisco. Can they keep it up?

San Francisco 49ers tight end George Kittle is off the injury report for the team's Week 3 game against the Denver Broncos.

The public still isn't buying the Jaguars as real contenders, but should we entering their date with the Chargers in Los Angeles?

San Francisco 49ers tight end George Kittle (calf) was a limited participant on Thursday.

San Francisco 49ers tight end George Kittle (groin) was a limited participant on Wednesday.

Travon Walker projects well this week, per our model. Who else should you add and start in IDP formats?

Former Houston Texans running back Marlon Mack was elevated to the San Francisco 49ers' active roster on Tuesday, ahead of Week 3's game against the Denver Broncos on Sunday Night Football.

How does our algorithm rank the AFC North before some key matchups in Week 3? How good are the Bills? And how high did the Jaguars jump?

San Francisco Giants running back Tyrion Davis-Price will miss "at least a few weeks," according to head coach Kyle Shanahan.

San Francisco 49ers quarterback Trey Lance has likely suffered a season-ending ankle injury Sunday, according to Adam Schefter of ESPN.

San Francisco 49ers quarterback Trey Lance (ankle) will not return to Sunday's Week 2 game against the Seattle Seahawks.

San Francisco 49ers quarterback Trey Lance was carted off of the field in the first quarter of Sunday's Week 2 game against the Seattle Seahawks.